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Ednrbs-l
Spontaneous Allele Detail
Nomenclature
Symbol: Ednrbs-l
Name: endothelin receptor type B; piebald lethal
MGI ID: MGI:1856149
Synonyms: sl
Gene: Ednrb  Location: Chr14:103814625-103844173 bp, - strand  Genetic Position: Chr14, 53.05 cM
Ednrbs-l/Ednrbs-l

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  (C3H/HeJ x C57BL/6)F2
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsSouthern blotting revealed that all of the coding exons of the gene were deleted. In addition, the transcript was undetectable by northern blotting in homozygous mice. (J:22206)
Inheritance:    Recessive
Phenotypes
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Disease models
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Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ednrb Mutation:  57 strains or lines available
References
Original:  J:5008 Lane PW, Association of megacolon with two recessive spotting genes in the mouse. J Hered. 1966 Jan-Feb;57(1):29-31
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory