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Ptpn6me-v
Spontaneous Allele Detail
Nomenclature
Symbol: Ptpn6me-v
Name: protein tyrosine phosphatase, non-receptor type 6; viable motheaten
MGI ID: MGI:1856074
Synonyms: Hcphme-v, mev, mev, motheaten viable, Ptpn6mev
Gene: Ptpn6  Location: Chr6:124720707-124738714 bp, - strand  Genetic Position: Chr6, 59.17 cM
Phenotype of the Ptpn6me-v/Ptpn6me-v mouse

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Spontaneous (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsA T-to-A transversion point mutation at a splice consensus site results in the use of two other cryptic sites. One site would result in five amino acids being deleted from the encoded protein and the other would include 69bp of intronic sequence in the transcript. (J:11892)
Inheritance:    Recessive
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ptpn6 Mutation:  12 strains or lines available
References
Original:  J:7531 Shultz LD, et al., Viable motheaten, a new allele at the motheaten locus. I. Pathology. Am J Pathol. 1984 Aug;116(2):179-92
All:  100 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory