Plp1^jp-rsh
Spontaneous Allele Detail

Summary

• Symbol: Plp1^jp-rsh
• Name: proteolipid protein (myelin) 1; rumpshaker
• MGI ID: MGI:1856067
• Synonyms: jp-rsh
• Gene: Plp1 Location: ChrX:135723420-135740482 bp, + strand Genetic Position: ChrX, 59.1 cM, cytoband F1-F2
• Alliance: Plp1^jp-rsh page

Mutation origin

• Strain of Origin: STOCK Rb(1.3)1Bnr

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Sequence analysis of cDNA from brain showed this allele involves a T-to-C transition in exon 4, changing codon 187 from isoleucine to threonine (p.I187T). (J:2126)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plp1 Mutation: 19 strains or lines available

References

• Original: J:14143 Cattanach BM, et al., Rump shaker, a new neurological mutation. Mouse News Lett. 1988;81:63-64
• All: 26 reference(s)