Hr^hr
Spontaneous Allele Detail

Summary

• Symbol: Hr^hr
• Name: lysine demethylase and nuclear receptor corepressor; hairless
• MGI ID: MGI:1856057
• Synonyms: hr, SKH-1
• Gene: Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
• Alliance: Hr^hr page

Hr^hr/Hr^hr mouse

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Viral insertion
• Mutation details: The hr allele is the result of a retroviral integration. Insertion of murine leukemia proviral sequences into intron 6 results in aberrant splicing of the gene. (J:9252, J:19624, J:92053)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	2 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Hr^hr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 17 strains available Cell Lines: 0 lines available
• Carrying any Hr Mutation: 84 strains or lines available

References

• Original: J:2405 Brooke HC, Hairless mice. J Hered. 1926;17(5):173-74
• All: 123 reference(s)