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Spontaneous Allele Detail
Symbol: Tbx15de-H
Name: T-box 15; droopy ear Harwell
MGI ID: MGI:1856015
Synonyms: Tbx14, Tbx8
Gene: Tbx15  Location: Chr3:99147697-99261575 bp, + strand  Genetic Position: Chr3, 43.03 cM
Pigmentation phenotype of the Tbx15de-H/Tbx15de-H ae/ae mouse

Show the 2 phenotype image(s) involving this allele.

Strain of Origin:  Not Specified
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
Mutation detailsBy comparing the sequence of a 1.3kb junction fragment amplified from a homozygous mutant to a public genome sequence, this allele was found to comprise a 216 kb deletion that extends from intron 1 to 148 kb downstream of the polyadenylation sequence, removing all but the first exon of the Tbx15 gene.
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tbx15 Mutation:  34 strains or lines available
Original:  J:233 Curry GA, Genetical and development studies on droopy-eared mice. J Embryol Exp Morphol. 1959 Mar;7(1):39-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory