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Myo5ad
Spontaneous Allele Detail
Nomenclature
Symbol: Myo5ad
Name: myosin VA; dilute
MGI ID: MGI:1856004
Synonyms: blue dilution, d, dv, Maltese dilution
Gene: Myo5a  Location: Chr9:75071015-75223688 bp, + strand  Genetic Position: Chr9, 42.26 cM
A homozygous a/a Myo5ad/ Myo5ad mouse with wild-type nonagouti black sibling

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  old mutant of the mouse fancy
Mutation
description
Allele Type:    Spontaneous
Mutation:    Viral insertion
 
Mutation detailsThis mutation is the result of the integration of ecotropic murine leukemia virus Emv-3 into a noncoding region of the Myo5ad gene. Reversions of Myo5ad to wild-type are caused by excision of the virus leaving exactly one long terminal repeat in place. (J:6587, J:7092, J:7751)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 107 strains available      Cell Lines: 0 lines available
Carrying any Myo5a Mutation:  134 strains or lines available
References
Original:  J:12958 Russell ES, A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. IV. the Nature of the Effects of Genic Substitution in Five Major Allelic Series. Genetics. 1949 Mar;34(2):146-66
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory