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Krt71Ca-J
Spontaneous Allele Detail
Summary
Symbol: Krt71Ca-J
Name: keratin 71; caracul Jackson
MGI ID: MGI:1855992
Gene: Krt71  Location: Chr15:101642384-101651532 bp, - strand  Genetic Position: Chr15, 57.0 cM
Alliance: Krt71Ca-J page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsSequence analysis identified the spontaneous deletion of asparagine codon 139 or 140, through the deletion of CAA / ACA / AAC from the AACAACAA sequence at codong nucleotides 415-422. The deleted codon is located in the alpha-helical rod domain. This molecular lesion is the same that has been identified in Krt71Ca-Rin, Krt71Ca-9J, and Krt71Ca-10J. (J:86407)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt71 Mutation:  43 strains or lines available
References
Original:  J:161346 Dickie MM, Origin of Krt71Ca-J on C57BL/6J. Mouse News Lett. 1966;34:30-31
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory