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Lystbg-2J
Spontaneous Allele Detail
Nomenclature
Symbol: Lystbg-2J
Name: lysosomal trafficking regulator; beige 2 Jackson
MGI ID: MGI:1855970
Gene: Lyst  Location: Chr13:13764982-13953388 bp, + strand  Genetic Position: Chr13, 5.28 cM
Mutation
origin
Strain of Origin:  Yellow stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsThis allele was identified by a noncomplementation test with Lystbg. Quantitative reverse transcription showed the molecular fault in the Lystbg-2J mutation may be an intronic retrotransposition event causing a five-fold decrease in transcription and mRNA instability. (J:34205)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lyst Mutation:  153 strains or lines available
References
Original:  J:65327 Lane PW, bg-beige and bg<2J> - beige-2J. Mouse News Lett. 1962;26:35
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory