About   Help   FAQ
Lystbg
Radiation induced Allele Detail
Summary
Symbol: Lystbg
Name: lysosomal trafficking regulator; beige
MGI ID: MGI:1855968
Synonyms: 30B/22B, bg, CHS mice
Gene: Lyst  Location: Chr13:13764982-13953388 bp, + strand  Genetic Position: Chr13, 5.28 cM
Alliance: Lystbg page
Mutation
origin
Strain of Origin:  C3H/Rl
Mutation
description
Allele Type:    Radiation induced
Mutation:    Transposon insertion
 
Mutation detailsThis allele is an insertion of a partial LINE 1 repetitive element into an intron of the gene. The insertion included only the most 3' 1097 bp of the element producing a frameshift mutation resulting in a truncated protein predicted to be missing the last 1442 amino acids. (J:33734, J:41243)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 6 assay results
In Structures Affected by this Mutation: 6 anatomical structures
Tumor Data
List all tumor models in MMHCdb carrying Lystbg
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Lyst Mutation:  154 strains or lines available
References
Original:  J:29744 Kelly EM, Beige, bg. Mouse News Lett. 1957;16:36
All:  129 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
11/15/2022
MGI 6.22
The Jackson Laboratory