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Tyrp1B-lt
Spontaneous Allele Detail
Summary
Symbol: Tyrp1B-lt
Name: tyrosinase-related protein 1; light
MGI ID: MGI:1855962
Gene: Tyrp1  Location: Chr4:80752360-80769956 bp, + strand  Genetic Position: Chr4, 37.89 cM
Alliance: Tyrp1B-lt page
Tyrp1B-lt/Tyrp1B-lt

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C58
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA C-to-T transition at coding nucleotide 112 is predicted to result in an arginine to cysteine substitition at codon 38 (p.R38C). (J:1086)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Tyrp1 Mutation:  162 strains or lines available
References
Original:  J:13061 MacDOWELL EC, 'Light'--a new mouse color. J Hered. 1950 Feb;41(2):35-6
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory