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Tcp10a Gene Detail
Summary
  • Symbol
    Tcp10a
  • Name
    t-complex protein 10a
  • Synonyms
    D17Leh66A, D17Leh66aa, Gm10326, T66A-a, Tcp-10a
  • Feature Type
    protein coding gene
  • IDs
    MGI:98541
    NCBI Gene: 21461
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:7592055-7613259 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 4.72 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    11
  • RFLP
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98541
 protein coding gene Chr17:7592045-7613373 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023159
 protein coding gene Chr17:11073057-11084510 (+)
A/J MGP_AJ_G0023093
 protein coding gene Chr17:4814448-4886973 (+)
AKR/J MGP_AKRJ_G0023096
 protein coding gene Chr17:10795304-10804135 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0021074
 protein coding gene Chr17:9061083-9081860 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0022821
 protein coding gene Chr17:5055383-5078101 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0023029
 protein coding gene Chr17:4985079-5019088 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022949
 protein coding gene Chr17:4973769-4982856 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023598
 protein coding gene Chr17:10701540-11077242 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0021944
 protein coding gene Chr17:4464064-4483227 (-)
WSB/EiJ MGP_WSBEiJ_G0022419
 protein coding gene Chr17:4684183-4706611 (+)



Homology
more
  • Human Ortholog
    TCP10L, t-complex 10 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCP10L, t-complex 10 like
  • Synonyms
    C21orf77, LINC00846, PRED77, TCP10A-1, TCP10A-2
  • Links
    NCBI Gene ID: 140290
    neXtProt AC: NX_Q8TDR4
    UniProt: Q8TDR4

  • Chr Location
    21q22.11; chr21:32497967-32587373 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    330 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 21461 NCBI Gene Model | MGI Sequence Detail 21205 C57BL/6J ±  kb
transcript NR_046291 RefSeq | MGI Sequence Detail 2466 ZRU/MplStud  
polypeptide NP_035683 RefSeq | MGI Sequence Detail 438 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR009852 Centromere protein J, C-terminal domain
    IPR047002 T-complex protein 10, C-terminal domain superfamily
    IPR026581 T-complex protein 10 family
Molecular
Reagents
less
  • All nucleic 31
    Genomic 19
    cDNA 11
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14812, MGD-MRK-14832, MGD-MRK-4530, MGI:3714485
References
more
  • Summaries
    All 373
    Diseases 6
    Gene Ontology 2
    Phenotypes 330
  • Earliest
    J:7328 Rohme D, et al., Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell. 1984 Mar;36(3):783-8
  • Latest
    J:346702 Colombi I, et al., Heterogeneous subpopulations of GABA(A)R-responding neurons coexist across neuronal network scales and developmental stages in health and disease. iScience. 2024 Apr 19;27(4):109438
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory