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Prim2 Gene Detail
Summary
  • Symbol
    Prim2
  • Name
    DNA primase, p58 subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:97758
    NCBI Gene: 19076
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:33492891-33708876 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 12.70 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1356 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97758
 protein coding gene Chr1:33492889-33708876 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015901
 protein coding gene Chr1:31808960-32032188 (-)
A/J MGP_AJ_G0015885
 protein coding gene Chr1:31046229-31267585 (-)
AKR/J MGP_AKRJ_G0015841
 protein coding gene Chr1:31405307-31631391 (-)
BALB/cJ MGP_BALBcJ_G0015839
 protein coding gene Chr1:30680893-30908858 (-)
C3H/HeJ MGP_C3HHeJ_G0015673
 protein coding gene Chr1:31596499-31825160 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016292
 protein coding gene Chr1:33275099-33511629 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014014
 protein coding gene Chr1:28223876-28437805 (-)
CAST/EiJ MGP_CASTEiJ_G0015253
 protein coding gene Chr1:31447437-31673619 (-)
CBA/J MGP_CBAJ_G0015644
 protein coding gene Chr1:34173808-34413707 (-)
DBA/2J MGP_DBA2J_G0015745
 protein coding gene Chr1:30375961-30595160 (-)
FVB/NJ MGP_FVBNJ_G0015747
 protein coding gene Chr1:29929413-30145517 (-)
LP/J MGP_LPJ_G0015815
 protein coding gene Chr1:32118484-32372030 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015767
 protein coding gene Chr1:36470482-36703512 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016339
 protein coding gene Chr1:31380286-31602016 (-)
PWK/PhJ MGP_PWKPhJ_G0015036
 protein coding gene Chr1:30091749-30321520 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014819
 protein coding gene Chr1:31368867-31590344 (-)
WSB/EiJ MGP_WSBEiJ_G0015315
 protein coding gene Chr1:31373122-31590610 (-)



Homology
more
  • Human Ortholog
    PRIM2, DNA primase subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRIM2, DNA primase subunit 2
  • Synonyms
    p58, PRIM2A
  • Links
    NCBI Gene ID: 5558
    neXtProt AC: NX_P49643
    UniProt: P49643

  • Chr Location
    6p11.2; chr6:57221540-57646850 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1050
  • Tissues
    110
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026134 Ensembl Gene Model | MGI Sequence Detail 215986 C57BL/6J ±  kb
transcript ENSMUST00000027312 Ensembl | MGI Sequence Detail 1975 Not Applicable  
polypeptide ENSMUSP00000027312 Ensembl | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13609, MGI:2138206
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:22339 Prussak CE, et al., Mouse primase p49 subunit molecular cloning indicates conserved and divergent regions. J Biol Chem. 1989 Mar 25;264(9):4957-63
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory