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Hoxa7 Gene Detail
Summary
  • Symbol
    Hoxa7
  • Name
    homeobox A7
  • Synonyms
    Hox-1.1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96179
    NCBI Gene: 15404
  • Member of
    Hoxa cluster
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:52191471-52198757 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 25.40 cM
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96179
 protein coding gene Chr6:52191471-52198834 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030746
 protein coding gene Chr6:51455699-51463029 (-)
A/J MGP_AJ_G0030715
 protein coding gene Chr6:49050333-49057698 (-)
AKR/J MGP_AKRJ_G0030642
 protein coding gene Chr6:50756779-50764109 (-)
BALB/cJ MGP_BALBcJ_G0030727
 protein coding gene Chr6:49411002-49418349 (-)
C3H/HeJ MGP_C3HHeJ_G0030440
 protein coding gene Chr6:50765811-50773168 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031182
 protein coding gene Chr6:52591983-52599344 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028388
 protein coding gene Chr6:46698147-46705531 (-)
CAST/EiJ MGP_CASTEiJ_G0029843
 protein coding gene Chr6:50580763-50588132 (-)
CBA/J MGP_CBAJ_G0030414
 protein coding gene Chr6:54789926-54798490 (-)
DBA/2J MGP_DBA2J_G0030564
 protein coding gene Chr6:48972764-48980111 (-)
FVB/NJ MGP_FVBNJ_G0030516
 protein coding gene Chr6:48583234-48591694 (-)
LP/J MGP_LPJ_G0030649
 protein coding gene Chr6:51434382-51441712 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030550
 protein coding gene Chr6:57420801-57428136 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031212
 protein coding gene Chr6:50685454-50692784 (-)
PWK/PhJ MGP_PWKPhJ_G0029556
 protein coding gene Chr6:48596646-48604059 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029390
 protein coding gene Chr6:50020857-50028229 (-)
WSB/EiJ MGP_WSBEiJ_G0029920
 protein coding gene Chr6:50701595-50708945 (-)



Homology
more
  • Human Ortholog
    HOXA7, homeobox A7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HOXA7, homeobox A7
  • Synonyms
    ANTP, HOX1, HOX1.1, HOX1A
  • Links
    NCBI Gene ID: 3204
    neXtProt AC: NX_P31268
    UniProt: P31268

  • Chr Location
    7p15.2; chr7:27153716-27157936 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotypes from multigenic genotypes
    14 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and grossly normal with no apparent skeletal defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    997
  • Tissues
    194
  • cDNA Data
    39
  • Literature Summary
    61
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 15404 NCBI Gene Model | MGI Sequence Detail 7287 C57BL/6J ±  kb
transcript NM_001419272 RefSeq | MGI Sequence Detail 2622 ZRU/MplStud  
polypeptide P02830 UniProt | EBI | MGI Sequence Detail 229 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    Genomic 24
    cDNA 40
    Primer pair 11
    Other 13

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-10815, MGD-MRK-10880, MGI:2141621
References
more
  • Summaries
    All 124
    Developmental Gene Expression 61
    Gene Ontology 9
    Phenotypes 14
  • Earliest
    J:7833 Colberg-Poley AM, et al., Structural analysis of murine genes containing homoeo box sequences and their expression in embryonal carcinoma cells. Nature. 1985 Apr 25-May 1;314(6013):713-8
  • Latest
    J:322321 Catela C, et al., Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory