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F8a Gene Detail
Summary
  • Symbol
    F8a
  • Name
    factor 8-associated gene A
  • Synonyms
    DXUcsf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:95474
    NCBI Gene: 14070
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72271912-72274401 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.29 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95474
 protein coding gene ChrX:72271897-72274401 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035803
 protein coding gene ChrX:68952079-68954583 (+)
A/J MGP_AJ_G0035784
 protein coding gene ChrX:69154074-69156578 (+)
AKR/J MGP_AKRJ_G0035710
 protein coding gene ChrX:70977789-70980293 (+)
BALB/cJ MGP_BALBcJ_G0035771
 protein coding gene ChrX:68211314-68213818 (+)
C3H/HeJ MGP_C3HHeJ_G0035477
 protein coding gene ChrX:69442219-69444723 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036302
 protein coding gene ChrX:71077208-71079712 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034768
 protein coding gene ChrX:54768070-54770560 (+)
CBA/J MGP_CBAJ_G0035450
 protein coding gene ChrX:73009762-73012266 (+)
DBA/2J MGP_DBA2J_G0035608
 protein coding gene ChrX:68637171-68639675 (+)
FVB/NJ MGP_FVBNJ_G0035552
 protein coding gene ChrX:67966073-67968577 (+)
LP/J MGP_LPJ_G0035694
 protein coding gene ChrX:69786415-69788919 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035589
 protein coding gene ChrX:75576401-75578905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036323
 protein coding gene ChrX:68797262-68799766 (+)
PWK/PhJ MGP_PWKPhJ_G0034467
 protein coding gene ChrX:52791950-52794454 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034301
 protein coding gene ChrX:55682399-55684901 (+)
WSB/EiJ MGP_WSBEiJ_G0034907
 protein coding gene ChrX:68078704-68081209 (+)



Homology
more
  • Human Ortholog
    F8A1, coagulation factor VIII associated 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    F8A1, coagulation factor VIII associated 1
  • Synonyms
    DXS522E, F8A, HAP40
  • Links
    NCBI Gene ID: 8263
    neXtProt AC: NX_P23610
    UniProt: P23610

  • Chr Location
    Xq28; chrX:154886355-154888061 (+)  GRCh38
  • Human Ortholog
    F8A2, coagulation factor VIII associated 2
  • Synonyms
    HAP40
  • Links
    NCBI Gene ID: 474383
    neXtProt AC: NX_P23610
    UniProt: P23610

  • Chr Location
    Xq28; chrX:155382095-155383801 (+)  GRCh38
  • Human Ortholog
    F8A3, coagulation factor VIII associated 3
  • Synonyms
    HAP40
  • Links
    NCBI Gene ID: 474384
    neXtProt AC: NX_P23610
    UniProt: P23610

  • Chr Location
    Xq28; chrX:155456914-155458620 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    780
  • Tissues
    10
  • cDNA Data
    20
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14070 NCBI Gene Model | MGI Sequence Detail 2490 C57BL/6J ±  kb
transcript NM_007978 RefSeq | MGI Sequence Detail 2490 ZRU/MplStud  
polypeptide Q00558 UniProt | EBI | MGI Sequence Detail 381 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    Genomic 14
    cDNA 22
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-9240, MGD-MRK-9695, MGI:2147930
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:10466 Levinson B, et al., A transcribed gene in an intron of the human factor VIII gene. Genomics. 1990 May;7(1):1-11
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory