Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mastltm1.2Mama
Name:	microtubule associated serine/threonine kinase-like; targeted mutation 1.2, Marcos Malumbres
MGI ID:	MGI:5556127
Synonyms:	Mastl(-)
Gene:	Mastl  Location: Chr2:23006549-23046036 bp, - strand  Genetic Position: Chr2, 15.23 cM
Alliance:	Mastltm1.2Mama page

Germline Transmission:	Earliest citation of germline transmission: J:201971
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted in intron 3 and an FRT flanked neo cassette and loxP site were inserted in intron 4 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 4. (J:201971)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mastl Mutation:	36 strains or lines available

Original:	J:201971 Alvarez-Fernandez M, et al., Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17374-9
All:	1 reference(s)