Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nme8tm1.1Arte
Name:	NME/NM23 family member 8; targeted mutation 1.1, TaconicArtemis
MGI ID:	MGI:5550546
Synonyms:	Sptrx-2-
Gene:	Nme8  Location: Chr13:19829248-19881964 bp, - strand  Genetic Position: Chr13, 7.0 cM, cytoband A3.3
Alliance:	Nme8tm1.1Arte page

Germline Transmission:	Earliest citation of germline transmission: J:205172
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Nucleotide substitutions   Mutation details: The conserved WCGPC site in exon 4 was mutated to WSGPS. An FRT flanked neo-cassette was inserted downstream of exon 4 and then removed via recombinase, resulting in a single FRT site in intron 4. (J:205172)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nme8 Mutation:	38 strains or lines available

Original:	J:205172 Smith TB, et al., Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress. Free Radic Biol Med. 2013 Dec;65:872-81
All:	1 reference(s)