Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pon3tm1Lus
Name:	paraoxonase 3; targeted mutation 1, Aldons J Lusis
MGI ID:	MGI:5544271
Gene:	Pon3  Location: Chr6:5220852-5256286 bp, - strand  Genetic Position: Chr6, 1.99 cM
Alliance:	Pon3tm1Lus page

Germline Transmission:	Earliest citation of germline transmission: J:204799
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Not Specified   Mutation details: No details provided. Western blot analysis confirmed the absence of protein expression in liver mitochondria. (J:204799)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pon3 Mutation:	24 strains or lines available

Original:	J:204799 Schweikert EM, et al., PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death. Cell Death Differ. 2012 Sep;19(9):1549-60
All:	2 reference(s)