Spo11tm3Rdco
Targeted Allele Detail
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Symbol: |
Spo11tm3Rdco |
Name: |
SPO11 initiator of meiotic double stranded breaks; targeted mutation 3, R Daniel Camerini-Otero |
MGI ID: |
MGI:5538689 |
Gene: |
Spo11 Location: Chr2:172819493-172835369 bp, + strand Genetic Position: Chr2, 95.64 cM, cytoband H4
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Alliance: |
Spo11tm3Rdco page
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Absence of germ cells beyond the spermatocyte stage and small ovaries with diminished number of follicles in Spo11tm1.1Gvpc/Spo11tm1.1Gvpc mice and absence of ovarian follicles in Spo11tm1.1Gvpc/Spo11tm3Rdco mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:202231
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Exons 2 through 6 were deleted. This allele results in the absence of protein expression. (J:202231)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Spo11 Mutation: |
20 strains or lines available
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Original: |
J:202231 Smagulova F, et al., Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele. BMC Genomics. 2013;14:493 |
All: |
2 reference(s) |
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