Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Izumo1rtm1.1Salb
Name:	IZUMO1 receptor, JUNO; targeted mutation 1.1, J Michael Salbaum
MGI ID:	MGI:5538512
Gene:	Izumo1r  Location: Chr9:14797110-14815245 bp, - strand  Genetic Position: Chr9, 4.42 cM
Alliance:	Izumo1rtm1.1Salb page

Germline Transmission:	Earliest citation of germline transmission: J:202519
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The first two coding exons were flanked by loxP sites and the second loxP site was followed by a neomycin resistance gene and a third loxP site. Properly targeted mice were crossed to mice expressing cre in oocytes to excise the selection cassette and the two floxed exons. (J:202519)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Izumo1r Mutation:	23 strains or lines available

Original:	J:202519 Salbaum JM, et al., Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation. Biochim Biophys Acta. 2013 Oct;1832(10):1653-61
All:	2 reference(s)