Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Fgl1tm1Cuko Name: fibrinogen-like protein 1; targeted mutation 1, Chinweike Ukomadu MGI ID: MGI:5510996 Gene: Fgl1  Location: Chr8:41644471-41668193 bp, - strand  Genetic Position: Chr8, 23.89 cM Alliance: Fgl1tm1Cuko page

Lipid accumulation in Fgl1tm1Cuko/Fgl1tm1Cuko livers Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:199844
Parent Cell Line:	PTL1 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6J)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin resistance cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein in the liver. (J:199844)

Schematic representation of the generation of the Fgl1tm1Cuko allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgl1 Mutation:	27 strains or lines available

Original:	J:199844 Demchev V, et al., Targeted deletion of fibrinogen like protein 1 reveals a novel role in energy substrate utilization. PLoS One. 2013;8(3):e58084
All:	2 reference(s)