Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Usp10tm1Fuj
Name:	ubiquitin specific peptidase 10; targeted mutation 1, Masahiro Fujii
MGI ID:	MGI:5498660
Synonyms:	Usp10delta
Gene:	Usp10  Location: Chr8:120637099-120684299 bp, + strand  Genetic Position: Chr8, 68.61 cM, cytoband E1
Alliance:	Usp10tm1Fuj page

Germline Transmission:	Earliest citation of germline transmission: J:194412
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was deleted. RT-PCR confirmed a peptide product consistent with 30 N-terminal amino acids and 11 amino acids from an "out of frame" exon 4 translation. Western blot analysis confirmed the absence of native protein. This allele was generated from Usp10tm2.1Fuj (J:194412)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Usp10 Mutation:	58 strains or lines available

Original:	J:194412 Takahashi M, et al., Stress granules inhibit apoptosis by reducing reactive oxygen species production. Mol Cell Biol. 2013 Feb;33(4):815-29
All:	2 reference(s)