Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Flrt2tm1.1Kln
Name:	fibronectin leucine rich transmembrane protein 2; targeted mutation 1.1, Rudiger Klein
MGI ID:	MGI:5495469
Gene:	Flrt2  Location: Chr12:95659000-95751989 bp, + strand  Genetic Position: Chr12, 46.44 cM
Alliance:	Flrt2tm1.1Kln page

Germline Transmission:	Earliest citation of germline transmission: J:196042
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin resistance cassette replaced the open reading frame in exon 2. Cre-mediated recombination removed the neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:196042)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Flrt2 Mutation:	45 strains or lines available

Original:	J:196042 Yamagishi S, et al., FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. EMBO J. 2011 Jul 20;30(14):2920-33
All:	4 reference(s)