Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cbx4tm1.2Gxu
Name:	chromobox 4; targeted mutation 1.2, Guo-Liang Xu
MGI ID:	MGI:5489932
Gene:	Cbx4  Location: Chr11:118968399-118977047 bp, - strand  Genetic Position: Chr11, 83.34 cM
Alliance:	Cbx4tm1.2Gxu page

Germline Transmission:	Earliest citation of germline transmission: J:194053
Parent Cell Line:	MPI-II (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 2 via homologous recombination. Flp and cre mediated recombination removed the neo cassette and exons 1 and 2. (J:194053)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cbx4 Mutation:	16 strains or lines available

Original:	J:194053 Liu B, et al., Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development. 2013 Feb;140(4):780-8
All:	2 reference(s)