Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rettm6.2Vpa
Name:	ret proto-oncogene; targeted mutation 6.2, Vassilis Pachnis
MGI ID:	MGI:5489748
Gene:	Ret  Location: Chr6:118128706-118174679 bp, - strand  Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
Alliance:	Rettm6.2Vpa page

Germline Transmission:	Earliest citation of germline transmission: J:195828
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette and exon 1. (J:195828)

Generation of the Rettm6.1Vpa and Rettm6.2Vpa alleles

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ret Mutation:	53 strains or lines available

Original:	J:195828 Almeida AR, et al., RET/GFRalpha signals are dispensable for thymic T cell development in vivo. PLoS One. 2012;7(12):e52949
All:	1 reference(s)