Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Macroh2a1tm1Mbou
Name:	macroH2A.1 histone; targeted mutation 1, Mathieu Boulard
MGI ID:	MGI:5485999
Gene:	Macroh2a1  Location: Chr13:56221435-56283439 bp, - strand  Genetic Position: Chr13, 30.06 cM, cytoband B2
Alliance:	Macroh2a1tm1Mbou page

Germline Transmission:	Earliest citation of germline transmission: J:195833
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced exon 2. Western blot anlaysis confirmed the absence of protein expression in the brain, liver, testis, spleen, kidney and thymus. (J:195833)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Macroh2a1 Mutation:	50 strains or lines available

Original:	J:195833 Boulard M, et al., Histone variant macroH2A1 deletion in mice causes female-specific steatosis. Epigenetics Chromatin. 2010;3(1):8
All:	2 reference(s)