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Prkcztm1.1Msg
Targeted Allele Detail
Summary
Symbol: Prkcztm1.1Msg
Name: protein kinase C, zeta; targeted mutation 1.1, Robert O Messing
MGI ID: MGI:5485241
Gene: Prkcz  Location: Chr4:155344586-155445818 bp, - strand  Genetic Position: Chr4, 86.17 cM, cytoband E2
Alliance: Prkcztm1.1Msg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:194398
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 9 was floxed and removed by cre-mediated recombination. Western blot analysis confirmed the absence of protein expression in the brain and kidney. (J:194398)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkcz Mutation:  43 strains or lines available
References
Original:  J:194398 Lee AM, et al., Prkcz null mice show normal learning and memory. Nature. 2013 Jan 17;493(7432):416-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory