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Kcnmb1tm1Ltor
Targeted Allele Detail
Summary
Symbol: Kcnmb1tm1Ltor
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 1; targeted mutation 1, Ligia Toro
MGI ID: MGI:5485152
Synonyms: beta1-
Gene: Kcnmb1  Location: Chr11:33913013-33923641 bp, + strand  Genetic Position: Chr11, 19.32 cM
Alliance: Kcnmb1tm1Ltor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:195657
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 and 3 were deleted. The absence of transcript expression was confirmed in aorta, uterus and bladder. (J:195657)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnmb1 Mutation:  14 strains or lines available
References
Original:  J:195657 Li M, et al., The beta1-subunit of the MaxiK channel associates with the thromboxane A2 receptor and reduces thromboxane A2 functional effects. J Biol Chem. 2013 Feb 1;288(5):3668-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory