Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Alkbh5tm1.1Klng
Name:	alkB homolog 5, RNA demethylase; targeted mutation 1.1, Arne Klungland
MGI ID:	MGI:5473894
Gene:	Alkbh5  Location: Chr11:60428509-60449338 bp, + strand  Genetic Position: Chr11, 37.81 cM
Alliance:	Alkbh5tm1.1Klng page

Germline Transmission:	Earliest citation of germline transmission: J:194218
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1. A neo cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the neo cassette. RNA in situ hybridization confirmed the absence of transcript expression. (J:194218)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Alkbh5 Mutation:	18 strains or lines available

Original:	J:194218 Zheng G, et al., ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10;49(1):18-29
All:	2 reference(s)