Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol: Cd200r1tm1Eakj Name: CD200 receptor 1; targeted mutation 1, Evelyn A Kurt-Jones MGI ID: MGI:5472130 Gene: Cd200r1  Location: Chr16:44586141-44615341 bp, + strand  Genetic Position: Chr16, 29.08 cM, cytoband B5 Alliance: Cd200r1tm1Eakj page

Decreased susceptibility of Cd200r1tm1Eakj/Cd200r1tm1Eakj mice to HSV-1 viral infection Show the 2 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:192198
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neo cassette replaced exon 1. Flow cytometry confirmed the absence of protein in macrophages. (J:192198)

Generation of the Cd200r1tm1Eakj allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd200r1 Mutation:	31 strains or lines available

Original:	J:192198 Soberman RJ, et al., CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2. PLoS One. 2012;7(10):e47740
All:	2 reference(s)