Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hoxb2tm2.2Fmr
Name:	homeobox B2; targeted mutation 2.2, Filippo M Rijli
MGI ID:	MGI:5470287
Synonyms:	Hoxb2del
Gene:	Hoxb2  Location: Chr11:96242458-96244846 bp, + strand  Genetic Position: Chr11, 59.85 cM
Alliance:	Hoxb2tm2.2Fmr page

Germline Transmission:	Earliest citation of germline transmission: J:193058
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted into the intron downstream of the translation start codon. An additional loxP site was inserted downstream of the translation stop codon. Flp-mediated recombination removed the neo cassette and left most of the coding sequence floxed. Cre-mediated recombination removed most of the coding sequence. (J:193058)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb2 Mutation:	12 strains or lines available

Original:	J:193058 Miguez A, et al., Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning. J Neurosci. 2012 Nov 28;32(48):17172-85
All:	1 reference(s)