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Abcb6tm1Pkr
Targeted Allele Detail
Summary
Symbol: Abcb6tm1Pkr
Name: ATP-binding cassette, sub-family B member 6; targeted mutation 1, Partha Krishnamurthy
MGI ID: MGI:5463225
Gene: Abcb6  Location: Chr1:75148361-75157036 bp, - strand  Genetic Position: Chr1, 38.62 cM, cytoband C3
Alliance: Abcb6tm1Pkr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190243
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 3, 4, and 5 were replaced with a neo cassette via homologous recombination. (J:190243)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcb6 Mutation:  41 strains or lines available
References
Original:  J:190243 Chavan H, et al., Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). J Biol Chem. 2012 Sep 14;287(38):32054-68
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory