Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Del(9Casp1-Casp4)1Bhk
Name:	deletion, Chr 9, Beverly H Koller 1
MGI ID:	MGI:5449892
Synonyms:	Casp1/Casp4tm1Bhk, Del1Bhk
Gene:	Del(9Casp1-Casp4)1Bhk  Location: unknown  Genetic Position: Chr9, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:189777
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intergenic deletion, Intragenic deletion   Del(9Casp1-Casp4)1Bhk involves 2 genes/genome features (Casp1, Casp4) View all   Mutation details: Recombination removed the entire coding regions of Casp1 and Casp4 along with 8 kb 5' of Casp1 and 6 kb 3' of Casp4. (J:189777)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(9Casp1-Casp4)1Bhk Mutation:	0 strains or lines available

Original:	J:189777 Kovarova M, et al., NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J Immunol. 2012 Aug 15;189(4):2006-16
All:	10 reference(s)