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Wwp1tm1Lmat
Targeted Allele Detail
Summary
Symbol: Wwp1tm1Lmat
Name: WW domain containing E3 ubiquitin protein ligase 1; targeted mutation 1, Lydia E Matesic
MGI ID: MGI:5449071
Gene: Wwp1  Location: Chr4:19608303-19708993 bp, - strand  Genetic Position: Chr4, 7.56 cM
Alliance: Wwp1tm1Lmat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190204
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
    A knock-out allele was generated. No details provided. (J:190204)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wwp1 Mutation:  62 strains or lines available
References
Original:  J:190204 Zhao L, et al., Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem Cells. 2011 Oct;29(10):1601-10
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory