Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol: Neu3tm1Yamk Name: neuraminidase 3; targeted mutation 1, Kazunori Yamaguchi MGI ID: MGI:5446783 Synonyms: Neu3tm1Myg Gene: Neu3  Location: Chr7:99460646-99477579 bp, - strand  Genetic Position: Chr7, 54.15 cM, cytoband F1 Alliance: Neu3tm1Yamk page

Decreased incidence of chemically induced colon tumors in Neu3tm1Yamk/Neu3tm1Yamk mice Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:189604
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neo cassette replaced part of exon 3. RT-PCR confirmed the absence of transcript expression. (J:189604)

Generation of the Neu3tm1Yamk allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Neu3 Mutation:	25 strains or lines available

Original:	J:189604 Yamaguchi K, et al., Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase. PLoS One. 2012;7(7):e41132
All:	12 reference(s)