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Cdx2tm1.2Aral
Targeted Allele Detail
Summary
Symbol: Cdx2tm1.2Aral
Name: caudal type homeobox 2; targeted mutation 1.2, Amy Ralston
MGI ID: MGI:5445745
Synonyms: Cdx2del
Gene: Cdx2  Location: Chr5:147237710-147244059 bp, - strand  Genetic Position: Chr5, 86.86 cM, cytoband G2-G3
Alliance: Cdx2tm1.2Aral page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189005
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and a loxP site and FRT flanked inverted neo cassette were inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exon 1. (J:189005)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdx2 Mutation:  22 strains or lines available
References
Original:  J:189005 Blij S, et al., Maternal Cdx2 is dispensable for mouse development. Development. 2012 Nov;139(21):3969-72
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory