Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Foxc2tm1.2Tsku Name: forkhead box C2; targeted mutation 1.2, Tsutomu Kume MGI ID: MGI:5443921 Synonyms: Foxc2delta Gene: Foxc2  Location: Chr8:121842910-121845634 bp, + strand  Genetic Position: Chr8, 70.33 cM Alliance: Foxc2tm1.2Tsku page

Ventricular septal defect and thin myocardium in Foxc2tm1.2Tsku/Foxc2tm1.2Tsku embryos Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:188816
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination of Foxc2tm1.1Tsku removed the coding sequence. RT-PCR confirmed the absence of transcript expression in embryos. (J:188816)

Generation of the Foxc2tm1.1Tsku and Foxc2tm1.2Tsku alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxc2 Mutation:	15 strains or lines available

Original:	J:188816 Sasman A, et al., Generation of conditional alleles for Foxc1 and Foxc2 in mice. Genesis. 2012 Oct;50(10):766-74
All:	2 reference(s)