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Med23tm1Berk
Targeted Allele Detail
Summary
Symbol: Med23tm1Berk
Name: mediator complex subunit 23; targeted mutation 1, Arnold J Berk
MGI ID: MGI:5441005
Gene: Med23  Location: Chr10:24745889-24789358 bp, + strand  Genetic Position: Chr10, Syntenic
Alliance: Med23tm1Berk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:188551
Parent Cell Line:  LW1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced part of exon 2 and all of exons 3 and 4 resulting in a 125 amino acid deletion. (J:125417)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Med23 Mutation:  73 strains or lines available
References
Original:  J:125417 Stevens JL, et al., Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit. Science. 2002 Apr 26;296(5568):755-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory