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Fstl1tm1.1Nju
Targeted Allele Detail
Summary
Symbol: Fstl1tm1.1Nju
Name: follistatin-like 1; targeted mutation 1.1, Model Animal Research Center of Nanjing University
MGI ID: MGI:5440894
Gene: Fstl1  Location: Chr16:37597417-37656878 bp, + strand  Genetic Position: Chr16, 26.48 cM
Alliance: Fstl1tm1.1Nju page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:187117
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 2. (J:188549)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fstl1 Mutation:  44 strains or lines available
References
Original:  J:187117 Xu J, et al., Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory