Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dhx58tm1Itl
Name:	DExH-box helicase 58; targeted mutation 1, inGenious Targeting Laboratory
MGI ID:	MGI:5439127
Gene:	Dhx58  Location: Chr11:100585710-100595097 bp, - strand  Genetic Position: Chr11, 63.52 cM
Alliance:	Dhx58tm1Itl page

Germline Transmission:	Earliest citation of germline transmission: J:187386
Parent Cell Line:	iTL IC1 (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaces exons 2 through 8. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:187386)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dhx58 Mutation:	36 strains or lines available

Original:	J:187386 Suthar MS, et al., The RIG-I-like Receptor LGP2 Controls CD8(+) T Cell Survival and Fitness. Immunity. 2012 Aug 24;37(2):235-48
All:	5 reference(s)