Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gemtm1.1Jgun
Name:	GTP binding protein overexpressed in skeletal muscle; targeted mutation 1.1, Jenny E Gunton
MGI ID:	MGI:5439008
Gene:	Gem  Location: Chr4:11704457-11714752 bp, + strand  Genetic Position: Chr4, 5.34 cM
Alliance:	Gemtm1.1Jgun page

Germline Transmission:	Earliest citation of germline transmission: J:187922
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed exon 2. RT-PCR confirmed the expression of a truncated transcript. (J:187922)

Schematic of the Gemtm1Jgun and Gemtm1.1Jgun alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gem Mutation:	15 strains or lines available

Original:	J:187922 Gunton JE, et al., Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling. PLoS One. 2012;7(6):e39462
All:	1 reference(s)