About   Help   FAQ
Pip5k1atm1.1Tba
Targeted Allele Detail
Summary
Symbol: Pip5k1atm1.1Tba
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha; targeted mutation 1.1, Tadashi Baba
MGI ID: MGI:5430936
Gene: Pip5k1a  Location: Chr3:94965841-95014241 bp, - strand  Genetic Position: Chr3, 40.74 cM
Alliance: Pip5k1atm1.1Tba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185835
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 was replaced with a floxed neo cassette. Cre-mediated recombination removed the neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:185835)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pip5k1a Mutation:  67 strains or lines available
References
Original:  J:185835 Hasegawa H, et al., Phosphatidylinositol 4-phosphate 5-kinase is indispensable for mouse spermatogenesis. Biol Reprod. 2012;86(5):136, 1-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory