Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fcgr2btm1.2Jsv
Name:	Fc receptor, IgG, low affinity IIb; targeted mutation 1.2, J Sjef Verbeek
MGI ID:	MGI:5427927
Synonyms:	Fcgr2btm1.2Sjv, FcgRIIBB6-
Gene:	Fcgr2b  Location: Chr1:170786186-170804116 bp, - strand  Genetic Position: Chr1, 78.02 cM
Alliance:	Fcgr2btm1.2Jsv page

Germline Transmission:	Earliest citation of germline transmission: J:179175
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed the neo cassette and exons 4 and 5. Flow cytometry confirmed the near absence of protein expression in B cells. (J:179175)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fcgr2b Mutation:	49 strains or lines available

Original:	J:179175 Boross P, et al., The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility. J Immunol. 2011 Aug 1;187(3):1304-13
All:	8 reference(s)