Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Casp6tm1.2Xen
Name:	caspase 6; targeted mutation 1.2, Taconic Biosciences
MGI ID:	MGI:5426933
Synonyms:	Casp6tm1Tac
Gene:	Casp6  Location: Chr3:129695074-129707752 bp, + strand  Genetic Position: Chr3, 59.5 cM, cytoband H1
Alliance:	Casp6tm1.2Xen page

Germline Transmission:	Earliest citation of germline transmission: J:147112
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: LoxP sequences flanking coding exons 1 to 4 and loxP sequences flanking the Neo expression cassette were targeted to Caspase 6 gene. In-vitro mediated cre-deleted resulted in knockout of coding exons 1 to 4 (or exons 2 to 5 if the first non-coding exon is included). (J:147112)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Casp6 Mutation:	17 strains or lines available

Original:	J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017;
All:	6 reference(s)