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Bcl11atm1.1Sbri
Targeted Allele Detail
Summary
Symbol: Bcl11atm1.1Sbri
Name: BCL11 transcription factor A; targeted mutation 1.1, Stefan Britsch
MGI ID: MGI:5320881
Gene: Bcl11a  Location: Chr11:24028056-24124123 bp, + strand  Genetic Position: Chr11, 14.41 cM
Alliance: Bcl11atm1.1Sbri page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184011
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neo cassette was inserted 3' of exon 1 and a loxP site was inserted 5' of exon 1 via homologous recombination. Cre mediated recombination exon 1. Protein expression was not detected in homozygous embryos. (J:184011)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11a Mutation:  42 strains or lines available
References
Original:  J:184011 John A, et al., Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory