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Stat1tm1.2Mmul
Targeted Allele Detail
Summary
Symbol: Stat1tm1.2Mmul
Name: signal transducer and activator of transcription 1; targeted mutation 1.2, Mathias Muller
MGI ID: MGI:5319175
Synonyms: Stat1delta
Gene: Stat1  Location: Chr1:52158599-52201024 bp, + strand  Genetic Position: Chr1, 26.81 cM
Alliance: Stat1tm1.2Mmul page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183580
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed exons 6 through 10 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the liver, lung and spleen. (J:183580)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stat1 Mutation:  72 strains or lines available
References
Original:  J:183580 Wallner B, et al., Generation of mice with a conditional Stat1 null allele. Transgenic Res. 2012 Feb;21(1):217-24
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory