Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Oit3tm1Zgh
Name:	oncoprotein induced transcript 3; targeted mutation 1, Ze-Guang Han
MGI ID:	MGI:5315854
Gene:	Oit3  Location: Chr10:59258782-59277601 bp, - strand  Genetic Position: Chr10, 29.54 cM, cytoband B3
Alliance:	Oit3tm1Zgh page

Germline Transmission:	Earliest citation of germline transmission: J:181913
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neo cassette replaced exons 1 and 2. Western blot analysis confirmed the absence of protein expression in the liver and kidney, (J:181913)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oit3 Mutation:	45 strains or lines available

Original:	J:181913 Yan B, et al., OIT3 deficiency impairs uric acid reabsorption in renal tubule. FEBS Lett. 2012 Mar 23;586(6):760-5
All:	2 reference(s)