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Rassf2tm1Dlim
Targeted Allele Detail
Summary
Symbol: Rassf2tm1Dlim
Name: Ras association (RalGDS/AF-6) domain family member 2; targeted mutation 1, Dae-Sik Lim
MGI ID: MGI:5314787
Gene: Rassf2  Location: Chr2:131834770-131872336 bp, - strand  Genetic Position: Chr2, 64.14 cM
Alliance: Rassf2tm1Dlim page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181952
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA puro cassette replaced exons 4 and 5. Western blot analysis confirmed the absence of protein expression in the liver, brain, lung, bone marrow, lymph node, spleen and testis. (J:181952)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rassf2 Mutation:  23 strains or lines available
References
Original:  J:181952 Song H, et al., Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice. EMBO J. 2012 Mar 7;31(5):1147-59
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory