Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrn1tm1.2Ndiv
Name:	neuritin 1; targeted mutation 1.2, Elly Nedivi
MGI ID:	MGI:5307918
Gene:	Nrn1  Location: Chr13:36909596-36918451 bp, - strand  Genetic Position: Chr13, 14.44 cM
Alliance:	Nrn1tm1.2Ndiv page

Germline Transmission:	Earliest citation of germline transmission: J:178970
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 2 and a loxP and FRT flanked neo cassette was inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3. (J:178970)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nrn1 Mutation:	18 strains or lines available

Original:	J:178970 Fujino T, et al., CPG15 regulates synapse stability in the developing and adult brain. Genes Dev. 2011 Dec 15;25(24):2674-85
All:	6 reference(s)