Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cbx8tm1.1Hko
Name:	chromobox 8; targeted mutation 1.1, Haruhiko Koseki
MGI ID:	MGI:5306630
Synonyms:	Cbx8delta
Gene:	Cbx8  Location: Chr11:118929262-118931739 bp, - strand  Genetic Position: Chr11, 83.33 cM, cytoband E2
Alliance:	Cbx8tm1.1Hko page

Germline Transmission:	Earliest citation of germline transmission: J:178955
Parent Cell Line:	M1/M-1 (ES Cell)
Strain of Origin:	(129 x C57BL/6)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Cre-mediated recombination removed exons 2 through 4. (J:178955)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cbx8 Mutation:	17 strains or lines available

Original:	J:178955 Tan J, et al., CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis. Cancer Cell. 2011 Nov 15;20(5):563-75
All:	1 reference(s)