Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tnfsf11tm1.2Htaka
Name:	tumor necrosis factor (ligand) superfamily, member 11; targeted mutation 1.2, Hiroshi Takayanagi
MGI ID:	MGI:5297062
Synonyms:	Tnfsf11delta
Gene:	Tnfsf11  Location: Chr14:78514886-78545483 bp, - strand  Genetic Position: Chr14, 41.26 cM
Alliance:	Tnfsf11tm1.2Htaka page

Germline Transmission:	Earliest citation of germline transmission: J:177557
Parent Cell Line:	A9 (ES Cell)
Strain of Origin:	(C57BL/6 x 129P2/OlaHsd)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Cre-mediated recombination removed the neo cassette and exons 3 and 4. (J:177557)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfsf11 Mutation:	30 strains or lines available

Original:	J:177557 Nakashima T, et al., Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med. 2011;17(10):1231-4
All:	4 reference(s)